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Antibacterial mechanism of ZnO nanoparticles under dark conditions
- Joe, Ara;
- Park, Se-Ho;
- Shim, Kyu-Dong;
- Kim, Da-Jung;
- Jhee, Kwang-Hwan;
- ... Jang, Eue-Soon;
- 외 3명
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224초록
To evaluate the antibacterial activity of zinc oxide (ZnO) in the absence of a light source, we examined three different types of nanoparticles that vary in size and the number of oxygen defect sites. Colony forming units (CFU) and various microscopic investigations revealed that the antibacterial activity of ZnO nanoparticles under dark conditions was not related to reactive oxygen species (ROS) generation and nanoparticles transfection, but depended on the ZnO attachment to bacterial cell walls and increasing concentrations of Zn2+ ions in the bacterial cytoplasm due to local dissolution of the attached ZnO. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
키워드
Zinc oxide; Antibacterial mechanism; Dark conditions; Reactive oxygen species; Zn2+ homeostasis; ZINC-OXIDE NANOPARTICLES; ESCHERICHIA-COLI; ANTIMICROBIAL ACTIVITY; TOXICITY; METALS; GROWTH
- 제목
- Antibacterial mechanism of ZnO nanoparticles under dark conditions
- 저자
- Joe, Ara; Park, Se-Ho; Shim, Kyu-Dong; Kim, Da-Jung; Jhee, Kwang-Hwan; Lee, Hyo-Won; Heo, Cheol-Ho; Kim, Hwan-Myung; Jang, Eue-Soon
- 발행일
- 2017-01-25
- 유형
- Article
- 권
- 45
- 페이지
- 430 ~ 439
- 언어
- ENG
- 출판사
- ELSEVIER SCIENCE INC
- 발행국가
- 미국
- 분량
- 10 페이지
- ISSN
- E 1876-794X
P 1226-086X